Senior Director of Evidence Generation working with the Evidence Generation team at BridgeBio Pharma. Focused on comparative effectiveness research and health outcomes innovation for rare diseases.
Responsibilities
Lead and design comparative effectiveness and health outcomes studies using real-world data (RWD), registries, claims databases, and clinical data sources
Develop strategic evidence plans that address clinical, payer, and patient stakeholder needs
Apply advanced study designs (e.g., propensity score matching, instrumental variables, target trial emulation) to generate credible, high-impact insights
Collaborate cross-functionally with Clinical Development, Health Economics and Outcomes Research (HEOR), Market Access, and Data Science teams to align evidence strategies with organizational priorities
Communicate findings in scientific forums, peer-reviewed publications, and internal stakeholder briefings
Serve as a subject matter expert in comparative effectiveness research within Medical Affairs
Represent the company in external collaborations, advisory boards, and industry working groups focused on RWE and methodological innovation
Provide mentorship and scientific guidance to evidence scientists and cross-functional partners
Requirements
Advanced degree (PhD, PharmD, MD, MPH, or MS) in Epidemiology, Health Economics, Biostatistics, Data Science, or related field
5–10+ years of experience in evidence generation, comparative effectiveness, or HEOR in a pharmaceutical, biotech, or academic setting
Demonstrated expertise in designing and executing RWD studies and comparative analyses
Strong track record of scientific publications and presentations
Excellent communication, strategic thinking, and stakeholder management skills.
Preferred experience in comparative effectiveness and statistical methodology
Ability to bridge technical analytical methods and clinical impact narratives
Benefits
Market leading compensation
401K with 100% employer match on first 3% & 50% on the next 2%
Employee stock purchase program
Pre-tax commuter benefits
Referral program with $2,500 award for hired referrals
Comprehensive health care with 100% premiums covered - no cost to you and dependents
Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
Hybrid work model - employees have the autonomy in where and how they do their work
Unlimited flexible paid time off - take the time that you need
Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents
Flex spending accounts & company-provided group term life & disability
Subsidized lunch via Forkable on days worked from our office
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