About the role

Senior Principal Scientist focusing on cardiovascular translational development and late-stage clinical research at Bristol Myers Squibb. Integrates laboratory science and project management to maximize drug development potential.

Responsibilities

Designs and implements program-specific development biomarker/translational plans
Responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.
Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable
Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs
Prepares and delivers internal and external translational/biomarker presentations
Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed
Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology
Works with TM laboratory scientists and academic TLs to address nonclinical translational questions as needed
Participates/leads post-hoc biomarker analysis and publication efforts
Supports regulatory submissions and regulatory interactions as needed
Participate in Diagnosis (PDx) biomarker assay development through collaboration with precision medicine group

PhD with 5–8+ years of translational medicine and clinical biomarker experience, including 5+ years supporting early‑ and/or late‑stage clinical programs in biotech or pharma.
Recognized expertise in translational biomarkers in cardiovascular or related disease areas, with experience in drug development and clinical trial initiation, conduct, and completion.
Experience interacting with CROs and thought leaders to manage projects, timelines, and deliverables.
Demonstrated scientific and project leadership experience, including working in cross‑functional teams, mentoring, and managing projects, with the ability to identify risks and implement contingency plans.
Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology, or patient segmentation hypotheses.
Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership, and externally as needed; recognizes and communicates cross‑functional issues across the organization.
Ability to support multiple projects in a fast‑paced, collaborative environment, with strong organizational skills, attention to detail, and accurate record keeping.

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays