Hybrid Executive Director, Global Project Leader – Oncology R&D

at AstraZeneca

• Job title: Executive Director, Global Project Leader – Oncology R&D
• Job type: Full Time
• Experience level: Senior
• Salary: $246,069 - $369,104 per year
• Degree requirement: Postgraduate Degree
• Location requirements: Hybrid, Gaithersburg, United States

About the role

• Executive Director Global Product Lead in Oncology R&D at AstraZeneca, accountable for multiple global product teams and strategic leadership in oncology drug development.

Responsibilities

• Join us at AstraZeneca as an Executive Director Global Product Lead (GPL) in Oncology R&D
• Lead and be accountable for multiple global cross-functional early global product teams across diverse biological mechanisms
• As the 'CEO' of the asset, you will have the chance to make a big impact
• Overall leadership and accountability of multiple global cross functional early global product teams across diverse biological mechanisms from candidate selection through Phase III investment decisions
• Accountable for the strategic leadership and execution for the product candidates
• Effectively communicate across a broad range of audiences
• Clearly articulate project specific strategies as it relates to the overall oncology strategy
• Leads global product teams from preclinical candidate selection through proof of concept leading to Phase III Investment decisions.
• Single point of accountability for the strategy, budget, timeline and execution of a portfolio of pre-clinical and clinical stage therapeutic candidates.
• Create integrated product development plans which are aligned with business objectives and are differentiated from competitor products.
• Lead and communicate the project development strategy at governance meetings to secure funding and endorsement of the strategy.
• Lead the global project team to effectively manage/mitigate/communicate risk.
• Monitor emerging data and pivot when deemed necessary.
• Maintain a high degree of team effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members.
• Maintain relationships with external investigators to ensure projects are consistent with evolving clinical.

Requirements

• Graduate degree such as a PhD, PharmD or an MD/PhD is required
• 10+ years experience leading oncology drug development
• Demonstrated success in developing oncology agents
• Industry experience in drug development including experience in early phase non-clinical and/or clinical drug development and regulatory knowledge
• Strong knowledge and understanding of the Oncology therapeutic area with experience in diverse biological mechanisms
• Broad understanding of the evolving clinical landscape in oncology
• Demonstrated experience leading and motivating teams in a highly matrixed environment
• Proven record of cultivating and managing internal and external cross-functional collaborations
• Demonstrated success in influencing colleagues and senior leaders in various departments
• Must demonstrate high integrity.
• Experience in the development of biologics is highly desirable.
• ADC/ IO/ Radio Conjugates (T cell engagers, immune redirecting agents, cell therapy, etc) development experience is highly desirable.
• Due diligence experience as GPLs often are required to participate in business development.

Benefits

• short-term incentive bonus opportunity
• eligibility to participate in our equity-based long-term incentive program (salaried roles)
• to receive a retirement contribution (hourly roles)
• commission payment eligibility (sales roles)
• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage